{"id":1257,"date":"2018-01-21T01:44:00","date_gmt":"2018-01-21T00:44:00","guid":{"rendered":"https:\/\/cosys.chimie.unistra.fr\/?page_id=1257"},"modified":"2024-01-15T07:37:22","modified_gmt":"2024-01-15T06:37:22","slug":"gold-catalysis","status":"publish","type":"page","link":"https:\/\/cosys.chimie.unistra.fr\/?page_id=1257","title":{"rendered":"Gold Catalysis"},"content":{"rendered":"<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-1668\" src=\"https:\/\/cosys.chimie.unistra.fr\/wp-content\/uploads\/2018\/04\/Gold-283x300.png\" alt=\"\" width=\"150\" height=\"159\" srcset=\"https:\/\/cosys.chimie.unistra.fr\/wp-content\/uploads\/2018\/04\/Gold-283x300.png 283w, https:\/\/cosys.chimie.unistra.fr\/wp-content\/uploads\/2018\/04\/Gold.png 595w\" sizes=\"auto, (max-width: 150px) 100vw, 150px\" \/><\/p>\n<h6><strong><span style=\"color: #004079;\">Cascade Reactions via Gold-Catalyzed Ammoniumation<\/span><\/strong><a href=\"https:\/\/onlinelibrary.wiley.com\/doi\/abs\/10.1002\/anie.200905341\"><sup><span style=\"color: #004079;\"><strong>1<\/strong><\/span><\/sup><\/a><\/h6>\n<p>With their exceptional carbophilic acidity, cationic gold(I) complexes are the catalysts of choice in the activation of unsaturated carbon-carbon bonds for nucleophilic addition. In this area, we have recently disclosed the efficiency of gold to promote the addition of secondary sulfonamides, as primary nucleophile, onto alkynes toward the preparation of elaborated nitrogenous compounds. The outcome of the reaction is efficiently controlled by the nature of a second nucleophile used to interact with the key vinyl-gold ammonium intermediate.<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-1759 size-full\" title=\"Cascade Reactions via Gold-Catalyzed Ammoniumation\" src=\"https:\/\/cosys.chimie.unistra.fr\/wp-content\/uploads\/2018\/04\/Diapositive3.png\" alt=\"\" width=\"768\" height=\"158\" srcset=\"https:\/\/cosys.chimie.unistra.fr\/wp-content\/uploads\/2018\/04\/Diapositive3.png 768w, https:\/\/cosys.chimie.unistra.fr\/wp-content\/uploads\/2018\/04\/Diapositive3-300x62.png 300w\" sizes=\"auto, (max-width: 768px) 100vw, 768px\" \/><\/p>\n<h6><strong><span style=\"color: #004079;\">Multifaceted-Gold Catalysis<\/span><\/strong><\/h6>\n<p style=\"text-align: justify;\">Gold cations are not only carbophilic (\u03c0) Lewis acid, they also exhibit a significant oxophilic character (\u03c3 Lewis).<a href=\"https:\/\/pubs.acs.org\/doi\/abs\/10.1021\/jo070579k\"><sup>2<\/sup><\/a> This double behavior offers the possibility to develop new synthetic methods via a \u201cmultifaceted catalysis\u201d process. Therefore, taking benefit of the both s and p Lewis acidities, various valuable compounds were obtained starting from alkynyl-oxirane, -aziridine or -azetidine derivatives in the presence of internal or external nucleophiles.<img loading=\"lazy\" decoding=\"async\" class=\"wp-image-1760 size-full aligncenter\" title=\"Multifaceted-Gold Catalysis\" src=\"https:\/\/cosys.chimie.unistra.fr\/wp-content\/uploads\/2018\/04\/Diapositive4.png\" alt=\"\" width=\"760\" height=\"134\" srcset=\"https:\/\/cosys.chimie.unistra.fr\/wp-content\/uploads\/2018\/04\/Diapositive4.png 760w, https:\/\/cosys.chimie.unistra.fr\/wp-content\/uploads\/2018\/04\/Diapositive4-300x53.png 300w\" sizes=\"auto, (max-width: 760px) 100vw, 760px\" \/><\/p>\n<h6><strong><span style=\"color: #004079;\">Polyoxometalate\/Gold\/Ligand Hybrids as Multifunctional Catalysts<\/span><\/strong><\/h6>\n<p>With Green Chemistry principles in mind (notably recyclability, atom economy, limiting waste and catalytic processes), this topic is aiming at efficiently prepare innovative materials issued from the assemblies of polyoxometalates (POM)\/gold(I\/III)\/organic ligands and apply them as new synergetic catalysts in relevant organic transformations.<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-1761 size-full\" title=\"Polyoxometalate\/Gold\/Ligand Hybrids as Multifunctional Catalysts\" src=\"https:\/\/cosys.chimie.unistra.fr\/wp-content\/uploads\/2018\/04\/Diapositive5.png\" alt=\"\" width=\"545\" height=\"145\" srcset=\"https:\/\/cosys.chimie.unistra.fr\/wp-content\/uploads\/2018\/04\/Diapositive5.png 545w, https:\/\/cosys.chimie.unistra.fr\/wp-content\/uploads\/2018\/04\/Diapositive5-300x80.png 300w\" sizes=\"auto, (max-width: 545px) 100vw, 545px\" \/><\/p>\n<h6><span style=\"color: #004079;\"><strong>Development of <em>N<\/em>-Heterocyclic Carbenes (NHC) Gold(I\/III) Catalysts<\/strong><\/span><\/h6>\n<p>In the collaboration with Dr Pierre de Fremont, we are designing new NHC chiral or achiral gold complexes for specific catalytic applications.<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-1762 size-full\" title=\"Development of N-Heterocyclic Carbenes (NHC) Gold(I\/III) Catalysts\" src=\"https:\/\/cosys.chimie.unistra.fr\/wp-content\/uploads\/2018\/04\/Diapositive6.png\" alt=\"\" width=\"607\" height=\"164\" srcset=\"https:\/\/cosys.chimie.unistra.fr\/wp-content\/uploads\/2018\/04\/Diapositive6.png 607w, https:\/\/cosys.chimie.unistra.fr\/wp-content\/uploads\/2018\/04\/Diapositive6-300x81.png 300w\" sizes=\"auto, (max-width: 607px) 100vw, 607px\" \/><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Cascade Reactions via Gold-Catalyzed Ammoniumation1 With their exceptional carbophilic acidity, cationic gold(I) complexes are the catalysts of choice in the activation of unsaturated carbon-carbon bonds for nucleophilic addition. In this area, we have recently disclosed the efficiency of gold to promote the addition of secondary sulfonamides, as primary nucleophile, onto alkynes toward the preparation of [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-1257","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/cosys.chimie.unistra.fr\/index.php?rest_route=\/wp\/v2\/pages\/1257","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cosys.chimie.unistra.fr\/index.php?rest_route=\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/cosys.chimie.unistra.fr\/index.php?rest_route=\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/cosys.chimie.unistra.fr\/index.php?rest_route=\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/cosys.chimie.unistra.fr\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=1257"}],"version-history":[{"count":23,"href":"https:\/\/cosys.chimie.unistra.fr\/index.php?rest_route=\/wp\/v2\/pages\/1257\/revisions"}],"predecessor-version":[{"id":3162,"href":"https:\/\/cosys.chimie.unistra.fr\/index.php?rest_route=\/wp\/v2\/pages\/1257\/revisions\/3162"}],"wp:attachment":[{"href":"https:\/\/cosys.chimie.unistra.fr\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=1257"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}